Research shows that the fetal nasal bone is absent in approximately 70% of all Down syndrome cases. With the Fetal Nasal Bone Assessment option added to the Ultra-Screen protocol, the detection rate for Down syndrome is raised to 95% and may eliminate the need to screen for Down syndrome beyond the first trimester. Fetal Nasal Bone Assessment is a non-invasive procedure performed between 11 weeks, one day and 13 weeks, 6 days gestation, usually during the patient’s NT ultrasound examination so no additional patient visits are required. Physicians and sonographers may become credentialed in fetal nasal bone assessment by attending a one-day seminar, which may also qualify for CME credits.